Author Topic: basic science  (Read 752 times)

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fear and loathing

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basic science
« on: December 28, 2017, 07:23:46 PM »
Proteins perform every aspect of your life for your (including your thoughts, hopes and dreams).

Now, humans are close to being able to bypass evolution in order to obtain new capabilities:

Quote

Scientists Are Designing Artisanal Proteins for Your Body

The human body makes tens of thousands of cellular proteins, each for a particular task. Now researchers have learned to create custom versions not found in nature.


https://www.nytimes.com/2017/12/26/science/protein-design-david-baker.html?hpw&rref=science&action=click&pgtype=Homepage&module=well-region&region=bottom-well&WT.nav=bottom-well

There is one significant mistake in the article, which states: "Proteins fold because each amino acid has an electric charge. "

Many amino acids have zero charge, namely all of the non-polar amino acids and the polar-uncharged amino acids at biological pH (~7.4).
« Last Edit: December 29, 2017, 01:31:09 PM by fear and loathing »

fear and loathing

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Re: basic science
« Reply #1 on: December 29, 2017, 03:19:20 PM »
It's a whole other problem to insert designer genes into gametes, and ultimately into organisms capable of reproducing.

Now, however, the probability has increased above absolute zero.

fear and loathing

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Re: basic science
« Reply #2 on: January 03, 2018, 11:28:25 AM »
cellular nano-machines in action:



https://youtu.be/8_24UyJc-qw?t=14

It's an animation, but not a cartoon. The depictions are very realistic.
« Last Edit: January 03, 2018, 11:31:02 AM by fear and loathing »

Offline NFL-Solomon

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Re: basic science
« Reply #3 on: March 28, 2018, 04:14:54 PM »
LOL, like F&L knows basic science.
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Offline NFL-Solomon

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Re: basic science
« Reply #4 on: April 11, 2018, 12:53:49 PM »
F*** you F&L!
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Offline NFL-Solomon

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Re: basic science
« Reply #5 on: April 11, 2018, 12:54:05 PM »
F*** you very much!
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Re: basic science
« Reply #6 on: April 11, 2018, 12:54:30 PM »
F*** you F&L!
And Again!
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Re: basic science
« Reply #7 on: April 14, 2018, 07:53:19 AM »
Hope you are in Hell.
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Re: basic science
« Reply #8 on: April 14, 2018, 07:53:37 AM »
Die F&L
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Offline BuccinGator

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Re: basic science
« Reply #9 on: April 19, 2018, 05:27:13 PM »
Die F&L

Meh, just wish for him to get punched in the face.
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Re: basic science
« Reply #10 on: April 19, 2018, 06:20:30 PM »
Meh, just wish for him to get punched in the face.

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Re: basic science
« Reply #11 on: April 26, 2018, 09:08:57 AM »
Meh, just wish for him to get punched in the face.
Can't be both?
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Re: basic science
« Reply #12 on: April 26, 2018, 09:09:42 AM »
Mamby-pamby gator
The punch in the face could be the CAUSE of death.
There, now you have been granted Wisdom.
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NuminousGuy

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Re: basic science
« Reply #13 on: June 13, 2018, 01:19:09 PM »
The current status of reinventing life using CRISPR:

problems:
Quote
A Crispr Conundrum: How Cells Fend Off Gene Editing
https://www.nytimes.com/2018/06/12/science/crispr-cancer-gene-editing.html


- basically: Human cells have molecular mechanisms to attempt to ward off cancer-causing mutations to their DNA. CRISPR-induced changes mimic such mutations.
progress:
Quote
The Little-Known Nonprofit Behind the CRISPR Boom   A DNA archive has been quietly connecting labs from Massachusetts to China to Iraq.


https://www.theatlantic.com/science/archive/2018/06/the-dna-depot-that-has-sent-crispr-to-62-countries/562370/


basically: a small, non-profit group of scientists is sharing the wherewithal for gene editing as a public service.

NuminousGuy

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Re: basic science
« Reply #14 on: June 13, 2018, 06:27:26 PM »
GlaxoSmithKline is attempting to design synthetic nanomachines:
Quote
The idea is to create implants the size of a grain of rice, or even smaller, that can be bolted directly onto nerves to treat diseases, augmenting or replacing drugs. With internal batteries to send tiny electric pulses, the implants could alter nerve signals to loosen up airways in asthma sufferers, for example, or reduce inflammation in the gut from Crohn’s disease.

https://www.bloomberg.com/news/articles/2016-06-09/only-one-big-drugmaker-is-working-on-a-nanobot-cure
This is the general approach I studied in my research: model machines after biological nanomachines.

NuminousGuy

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Re: basic science
« Reply #15 on: June 15, 2018, 01:36:27 PM »
mass, time and distance: Modern Physics
absolutely fascinating

There's a nice, new popular discourse: Seven Brief Lessons on Physics, by Carlo Rovelli.

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Re: basic science
« Reply #16 on: June 20, 2018, 10:06:03 PM »
“And when they nail my pimpled ass to the cross
I'll tell them I found Jesus that should throw them off
He goes by the name Jesus and steals hubcaps from cars
Oh Jesus can I borrow your crowbar?”

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Offline Fog

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Re: basic science
« Reply #17 on: June 20, 2018, 10:08:52 PM »
You made money
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Re: basic science
« Reply #18 on: June 21, 2018, 06:12:28 PM »
You made money
Just spreading the Gospel of Hooray for Boobies.
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Re: basic science
« Reply #19 on: June 23, 2018, 12:54:08 PM »
Just spreading the Gospel of Hooray for Boobies.

I thought that was Shick's job.
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Re: basic science
« Reply #20 on: June 23, 2018, 05:02:34 PM »
It's a whole other problem to insert designer genes into gametes, and ultimately into organisms capable of reproducing.

Now, however, the probability has increased above absolute zero.

 Yeah, heard those tight designer jeans really screw up your nads! Can't be choking those little swimmer out before they are deployed.  dbana
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Offline Misterfamous

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Re: basic science
« Reply #21 on: June 24, 2018, 10:10:34 PM »
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